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Prof. Guang ZHU

Research Interests | Teaching Assignments | Publications

Research Area

Structure-function of biomolecules, NMR spectroscopy, Drug design

Research Interests

Structural biology, Deoxyribonucleic acid (DNA) replication, Cancer, Chemical biology, Cellular and molecular mechanisms,

Teaching Assignments

2020-21 Fall: BIPH3010 - Advanced Biological Physics
2020-21 Fall: LIFS6113D - Current Topics in Biochemistry and Biophysics
2020-21 Fall: BIBU4850 - Biotechnology and Business Project Research
2020-21 Spring: BIBU4850 - Biotechnology and Business Project Research
2020-21 Spring: LIFS4960 - Biological Science Capstone Project
2020-21 Spring: LIFS4961 - Biochemistry and Cell Biology Capstone Project
2020-21 Spring: LIFS4963 - Biotechnology Capstone Project
2020-21 Spring: BIPH4010 - Principles of Quantitative Instrumentation
2020-21 Spring: SCIE1120 - Chemistry and Life
2019-20 Spring: LIFS4981 - Biochemistry and Cell Biology Project Research II
2019-20 Spring: BIPH4010 - Principles of Quantitative Instrumentation
2019-20 Spring: LIFS6111L - Life Science Postgraduate Student Seminar
2019-20 Spring: SCIE1120 - Chemistry and Life
2019-20 Spring: LIFS4963 - Biotechnology Capstone Project

Recent Publications


  • Geng, Yanyan; Liu, Changdong; Cai, Qixu; Luo, Zhipu; Miao, Haitao; Shi, Xiao; Xu, Naining; Fung, Chun Po; Choy, To To; Yan, Bing; Li, Ning; Qian, Peiyuan; Zhou, Bo; Zhu, Guang, "Crystal structure of parallel G-quadruplex formed by the two-repeat ALS-and FTD-related GGGGCC sequence", (2021)
  • Xu, Naining; Tian, Honglei; Fung, Chun Po; Lin, Yuntao; Zhu, Guang; Shen, Yuehong; Yang, Hongyu, "Quantitative evaluation and comparison of two prodrug-activating suicide gene therapies on oral squamous cell carcinoma", (2021)
  • Amin, Aftab; Wu, Rentian; Cheung, Man Hei; Scott, John F.; Wang, Ziyi; Zhou, Zijing; Liu, Changdong; Zhu, Guang; Wong, Chris Kong Chu; Yu, Zhiling; Liang, Chun, "An essential and cell-cycle-dependent ORC dimerization cycle regulates eukaryotic chromosomal DNA replication", (2020)
  • Xu, Naining; You, Yingying; Liu, Changdong; Balasov, Maxim; Lun, Lee Tung; Geng, Yanyan; Fung, Chun Po; Miao, Haitao; Tian, Honglei; Choy, To To; Shi, Xiao; Fan, Zhuming; Zhou, Bo; Akhmetova, Katarina; Din, Rahman Ud; Yang, Hongyu; Hao, Quan; Qian, Peiyuan; Chesnokov, Igor; Zhu, Guang, "Structural basis of DNA replication origin recognition by human Orc6 protein binding with DNA", (2020)
  • Zhu, Guang, "A chair-type G-quadruplex structure formed by a human telomeric variant DNA in K+ solution", (2019)

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