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Prof. Jiguang WANG

Research Interests | Current Research Activities | Teaching Assignments | Publications

Research Area

Computational Biolog; Bioinformatics; Machine Learning; Medical Image Analytics

Research Interests

Cancer Genomics; Cancer Evolution; Genomic Medicine;

Current Research Activities

Brain cancer; Brain AVM (arteriovenous malformation); Computational Pathology

Teaching Assignments

2020-21 Fall: LIFS4971 - Biochemistry and Cell Biology Project Research I
2020-21 Fall: LIFS4960 - Biological Science Capstone Project
2020-21 Fall: LIFS4973 - Biotechnology Project Research I
2020-21 Spring: BIEN4930 - Bioengineering Thesis Research
2020-21 Spring: LIFS4963 - Biotechnology Capstone Project
2020-21 Spring: LIFS4981 - Biochemistry and Cell Biology Project Research II
2020-21 Spring: LIFS4983 - Biotechnology Project Research II
2020-21 Spring: BIEN3320 - Data Science for Biology and Medicine
2020-21 Spring: LIFS4320 - Data Science for Biology and Medicine
2020-21 Spring: LIFS6116D - Current Topics in Genomics and Bioinformatics
2019-20 Spring: BIEN3320 - Data Science for Biology and Medicine
2019-20 Spring: LIFS4320 - Data Science for Biology and Medicine
2019-20 Spring: LIFS6116C - Current Topics in Genomics and Bioinformatics
2019-20 Spring: LIFS4983 - Biotechnology Project Research II
2019-20 Spring: SCIE1500 - Guided Study on Research I
2019-20 Summer: UROP1000 - Undergraduate Research Opportunities

Selected Publications

  • Scuoppo, Claudio; Wang, Jiguang; Persaud, Mirjana; Mittan, Sandeep K.; Basso, Katia; Pasqualucci, Laura; Rabadan, Raul; Inghirami, Giorgio; Grandori, Carla; Bosch, Francesc; Dalla-favera, Riccardo "Repurposing dasatinib for diffuse large B cell lymphoma", PNAS, v. 116, (34), August 2019, p. 16981-16986 (2019)
  • Hu, Huimin; Mu, Quanhua; Bao, Zhaoshi; Chen, Yiyun; Liu, Yanwei; Chen, Jing; Wang, Kuanyu; Wang, Zheng; Nam, Yoonhee; Jiang, Biaobin; Sa, Jason K; Cho, Hee-Jin; Her, Nam-Gu; Zhang, Chuanbao; Zhao, Zheng; Zhang, Ying; Zeng, Fan; Wu, Fan; Kang, Xun; Liu, Yuqing; Qian, Zenghui; Wang, Zhiliang; Huang, Ruoyu; Wang, Qiangwei; Zhang, Wei; Qiu, Xiaoguang; Li, Wenbin; Nam, Do-Hyun; Fan, Xiaolong; Wang, Jiguang (corresponding); Jiang, Tao "Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor", Cell, v. 175, (6), November 2018, p. 1665-1678 (2018)
  • Lee, Jin-Ku; Liu, Zhaoqi; Sa, Jason K.; Shin, Sang; Wang, Jiguang (co-first); Bordyuh, Mykola; Cho, Heejin; Elliott, Oliver; Chu, Timothy; Choi, Seung Won; Rosenbloom, Daniel I. S.; Lee, In-Hee; Shin, Yong Jae; Kang, Hyun Ju; Kim, Donggeon; Kim, Sun Young; Sim, Moon-Hee; Kim, Jusun; Lee, Taehyang; Seo, Yun Jee; Shin, Hyemi; Lee, Mijeong; Kim, Sung Heon; Kwon, Yong-Jun; Oh, Jeong-Woo; Song, Minsuk; Kim, Misuk; Kong, Doo-Sik; Choi, Jung Won; Seol, Ho Jun; Lee, Jung-Il; Kim, Seung Tae; Park, Joon Oh; Kim, Kyoung-Mee; Song, Sang-Yong; Lee, Jeong-Won; Kim, Hee-Cheol; Lee, Jeong Eon; Choi, Min Gew; Seo, Sung Wook; Shim, Young Mog; Zo, Jae Ill; Jeong, Byong Chang; Yoon, Yeup; Ryu, Gyu Ha; Kim, Nayoung K. D.; Bae, Joon Seol; Park, Woong-Yang; Lee, Jeongwu; Verhaak, Roel G. W.; Iavarone, Antonio; Lee, Jeeyun; Rabadan, Raul; Nam, Do-Hyun "Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy", Nature Genetics, v. 50, (10), October 2018, p. 1399-1411 (2018)
  • Lee, Jin-Ku; Wang, Jiguang (co-first); Sa, Jason K.; Ladewig, Erik; Lee, Hae-Ock; Lee, In-Hee; Kang, Hyun Ju; Rosenbloom, Daniel S.; Camara, Pablo G.; Liu, Zhaoqi; Van Nieuwenhuizen, Patrick; Jung, Sang Won; Choi, Seung Won; Kim, Junhyung; Chen, Andrew; Kim, Kyu-Tae; Shin, Sang; Seo, Yun Jee; Oh, Jin-Mi; Shin, Yong Jae; Park, Chul-Kee; Kong, Doo-Sik; Seol, Ho Jun; Blumberg, Andrew; Lee, Jung-Il; Iavarone, Antonio; Park, Woong-Yang; Rabadan, Raul; Nam, Do-Hyun "Spatiotemporal Genomic Architecture Informs Precision Oncology in Glioblastoma", Nature Genetics, v. 49, (4), March 2017, p. 594-599 (2017)
  • Wang, Jiguang; Cazzato, Emanuela; Ladewig, Erik; Frattini, Véronique; Zairis, Sakellarios; Abate, Francesco; Liu, Zhaoqi; Elliott, Oliver; Shin, Yongjae; Lee, Jinku; Lee, Inhee; Park, Woongyang; Eoli, Marica; Blumberg, Andrew J.; Lasorella, Anna; Nam, Dohyun; Finocchiaro, Gaetano; Iavarone, Antonio; Rabadan, Raul "Clonal evolution of glioblastoma under therapy", Nature Genetics, v. 48, (7), 2016, Jul, p. 768-776 (2016)
  • Ceccarelli, Michele; Barthel, Floris P.; Malta, Tathiane Maistro Aistro; Sabedot, Thaís S.; Salama, Sofie Reda; Murray, Bradley A.; Morozova, Olena A.; Newton, Yulia; Radenbaugh, Amie J.; Pagnotta, Stefano Maria; Anjum, Samreen; Wang, Jiguang; Manyam, Ganiraju C.; Zoppoli, Pietro; Ling, Shiyun; Rao, Arjun A.; Grifford, Mia; Cherniack, Andrew D.; Zhang, Hailei; Poisson, Laila M.; Carlotti, Carlos Gilberto; Tirapelli, Daniela Pretti Da Cunha; Rao, Arvind; Mikkelsen, Tom; Lau, Ching; Yung, Alfred; Rabadán, Raúl; Huse, Jason T.; Brat, Daniel J.; Lehman, Norman L.; Barnholtz-Sloan, Jill S.; Zheng, Siyuan; Hess, Kenneth R.; Rao, Ganesh; Meyerson, Matthew; Beroukhim, Rameen; Cooper, Lee A D; Akbani, Rehan; Wrensch, Margaret R.; Haussler, David H.; Aldape, Kenneth D.; Laird, Peter W.; Gutmann, David H.; Noushmehr, Houtan; Iavarone, Antonio; Verhaak, Roel G W "Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma", Cell, v. 164, (3), 2016, Jan, p. 550-563 (2016)
  • Pefanis, Evangelos; Wang, Jiguang (co-first); Rothschild, Gerson; Lim, Junghyun; Kazadi, David; Sun, Jianbo; Federation, Alexander J.; Chao, Jaime; Elliott, Oliver; Liu, Zhiping; Economides, Aris N.; Bradner., James E.; Rabadan, Raul; Basu, Uttiya "RNA exosome-regulated long non-coding RNA transcription controls super-enhancer activity", Cell, v. 161, (4), 2015, May, p. 774-789 (2015)
  • Pefanis, Evangelos; Wang, Jiguang (co-first); Chao, Jaime; Rothschild, Gerson; Lim, Junghyun; Rabadan, Raul; Economides, Aris N.; Basu, Uttiya "Noncoding RNA Transcription Targets AID to Divergently Transcribed Loci in B Cells", Nature, v. 514, (7522), 2014, Oct, p. 389-393 (2014)
  • Wang, Jiguang (corresponding); Khiabanian, Hossein; Rossi, Davide; Fabbri, Giulia; Gattei, Valter; Forconi, Francesco; Laurenti, Luca; Marasca, Roberto; Del Poeta, Giovanni; Foa, Robin; Pasqualucci, Laura; Gaidano, Gianluca Luca; Rabadan, Raul "Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemia", eLife, v. 3, 2014, Dec, Article Number e02869 (2014)
  • Zhang, Chao; Wang, Jiguang (co-first); Hanspers, Kristina; Xu, Dong; Chen, Luonan; Pico, Alexander R. "NOA: A cytoscape plugin for network ontology analysis", Bioinformatics, v. 29, (16), 2013, August, p, 2066-2067 (2013)
  • Wang, Jiguang; Huang, Qiang; Liu, Zhiping; Wang, Yong; Wu, Lingyun; Chen, Luonan; Zhang, Xiangsun "NOA: a novel Network Ontology Analysis method", Nucleic Acids Research, v. 39, (13), 2011, Jul, p. e87 (2011)
  • Wang, Yongcui; Wang, Jiguang; Yang, Zhixia; Deng, Naiyang "Sequence-based protein-protein interaction prediction via support vector machine", Journal of Systems Science and Complexity, v. 23, (5), October 2010, p. 1012-1023 (2010)
  • Wang, Jiguang; Zhang, Shihua; Wang, Yong; Chen, Luonan; Zhang, Xiangsun "Disease-Aging Network Reveals Significant Roles of Aging Genes in Connecting Genetic Diseases", PLoS Computational Biology, v. 5, (9), 2009, Sep, Article number e1000521 (2009)
  • Wang, Jiguang; Qiu, Yuqing; Wang, Ruisheng; Zhang, Xiangsun "Remarks on network community properties", Journal of Systems Science and Complexity, v. 21, (4), December 2008, p. 629-636 (2008)

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